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CHERG - Child Epidemiology Reference Group
Child Mortality and Morbidity
Underlying causes of child death
Effect of co-morbidity on child mortality
Country-level causes of child mortality
Failures in the “pathways to survival”
Incidence and sequelae of child morbidity
Maternal Mortality and Morbidity
Causes of maternal mortality
Incidence and sequelae of maternal morbidity
Risk Factors
Indoor and outdoor air pollution
IUGR and preterm birth as risk factors for morbidity/mortality
Micronutrient deficiencies and nutritional status
Birth spacing as a risk factor of maternal and child mortality
Program-related Evidence
Intervention effectiveness to reduce maternal/child mortality
Measurement of intervention coverage
Enhance the LiST methodology


Effect of co-morbidity on child mortality
The standard practice of attributing each death to a single cause ignores the fact that many deaths are associated with more than one condition, often with two or more infectious diseases such as malaria and pneumonia. It is critical to understand the proportion of child mortality that can be attributed to the combined occurrence of multiple conditions referred to as “co-morbidity”, the effect of co-morbidity on the probability of mortality, and risk factors for co-morbidity. This information is important for program and research priority-setting. A better understanding of the role of co-morbidity may alter our perceptions with regard to the importance or effectiveness of child health interventions. 

Methods and Expected Products
This activity involves creating a core investigators group which will be composed of several child health researchers who have led large-scale pediatric cohort studies.  The core investigators group will conduct a rigorous search for all available appropriate data sets of co-morbidity and child mortality. Results of the analysis will be used to estimate the impact of co-morbidity on child mortality. The final results will be published in a peer review journal and will be made publicly available on the project website, in addition to publication in a peer review journal. 

All work will be done in collaboration with the investigators of the datasets.  During the first two years of the grant the activities will be focused on forming the investigators group, establishing an agreed upon analysis plan and conducting initial analyses. It is expected that an interim report summarizing the first draft of analyses will be completed by December 2010.

Fischer Walker CL, Perin J, Liu JL, et al.Does comorbidity increase the risk of mortality among children under 3 years of age? BMJ Open 2013;3:e003457. doi:10.1136/bmjopen-2013-003457 

Fischer Walker CL, Perin J, Katz J, Tielsch JM,Black RE. Diarrhea as a risk factor for acute lower respiratory tract infections among young children in low income settings. Journal of Global Health. 2013; 3(1): 010402

Co-morbidity Study Overview, by Christa Fischer Walker and Jamie Perin

Untitled Document

Examination of Child in Benin

PowerPoint Presentation
Global Child Mortality: Estimates of Levels and Causes for 2000-2010

New Publications 
Born Too Small: National and regional estimates of babies born small for gestational age. Healthy Newborn Network Blog on new article in Lancet Global Health

PLOS Med Collection: Measuring Coverage in Maternal, Newborn, and Child Health

LiST Tool
Download the the Lives Saved Tool

Lives Saved Tool in 2013: BMC Public Health Special Issue